Pancreas
The pancreas is both an exocrine and endocrine gland.
The exocrine portion of the gland function is producing secretion that contains enzymes capable of hydrolyzing proteins, fats, and carbohydrates. islets of Langerhans of the gland, the pancreatic islets (The endocrine portion), produces the hormones insulin and glucagon, which play a key role in carbohydrate metabolism.
The exocrine portion of the gland function is producing secretion that contains enzymes capable of hydrolyzing proteins, fats, and carbohydrates. islets of Langerhans of the gland, the pancreatic islets (The endocrine portion), produces the hormones insulin and glucagon, which play a key role in carbohydrate metabolism.
It is is an elongated structure that lies in the epigastrium
and the left upper quadrant. It is soft and lobulated and situated on the
posterior abdominal wall behind the peritoneum. It crosses the transpyloric
plane. The pancreas is divided into a head, neck, body, and tail.
The head of the pancreas is disc shaped and lies within the concavity of the duodenum. the uncinate process,is A part of the head extends to the left behind the superior mesenteric vessels .
The head of the pancreas is disc shaped and lies within the concavity of the duodenum. the uncinate process,is A part of the head extends to the left behind the superior mesenteric vessels .
The neck which connects the head to the body is the
constricted portion of the pancreas and. It lies in front of the beginning of
the portal vein and the origin of the superior mesenteric artery from the
aorta.
The body runs upward and to the left across the midline . It
is somewhat triangular in cross section. The tail passes forward in the
splenicorenal ligament and comes in contact with the hilum of the spleen
Relations
■■
Anteriorly: From right to left: the transverse colon and the attachment of the
transverse mesocolon, the lesser sac, and the stomach
■■
Posteriorly: From right to left: the bile duct, the portal and splenic veins,
the inferior vena cava, the aorta, the origin of the superior mesenteric
artery, the left psoas muscle, the left suprarenal gland, the left kidney, and
the hilum of the spleen
Trauma
of the Pancreas
The pancreas is is well protected because it is deeply
placed within the abdomen and protected
by the costal margin and the anterior abdominal wall. However, blunt trauma,
such as in a sports injury when a sudden blow to the abdomen occurs, can
compress and tear the pancreas against the vertebral column. The pancreas is
most commonly damaged by gunshot or stab wounds. Damaged pancreatic tissue
releases activated pancreatic enzymes that produce the signs and symptoms of
acute peritonitis.
Cancer
of the Head of the Pancreas and the Bile Duct
cancer of the head of the pancreas often causes obstructive
jaundice Because of the close relation of the head of the pancreas to the bile
duct,.
The
Pancreatic Tail and Splenectomy
The presence of the tail of the pancreas in the
splenicorenal ligament sometimes results in its damage during splenectomy. The
damaged pancreas releases enzymes that start to digest surrounding tissues,
with serious consequences
Diagnosis
of Pancreatic Disease
The deep location of the pancreas sometimes gives rise to
problems of diagnosis for the following reasons:
■■
Pain from the pancreas is commonly referred to the back.
■■
Because the pancreas lies behind the stomach and transverse colon, disease of
the gland can be confused with that of the stomach or transverse colon.
■■
Inflammation of the pancreas can spread to the peritoneum forming the posterior
wall of the lesser sac. This in turn can lead to adhesions and the closing off
of the lesser sac to form a pseudocyst.
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